Alterations of blood flow pattern after triple stent endovascular treatment of saccular abdominal aortic aneurysm: a porcine model.

ABSTRACT Objective: to determine the blood flow pattern changes after endovascular treatment of saccular abdominal aortic aneurysm with triple stent. Methods: we conducted a hemodynamic study of seven Landrace and Large White pigs with saccular aneurysms of the infrarenal abdominal aorta artificially produced according to the technique described. The animals were subjected to triple stenting for endovascular aneurysm. We evaluated the pattern of blood flow by duplex scan before and after stent implantation. We used the non-paired Mann-Whitney test for statistical analysis. Results: there was a significant decrease in the average systolic velocity, from 127.4cm/s in the pre-stent period to 69.81cm/s in the post-stent phase. There was also change in the flow pattern from turbulent in the aneurysmal sac to laminate intra-stent. Conclusion: there were changes in the blood flow pattern of saccular abdominal aortic aneurysm after endovascular treatment with triple stent.

摘要 研究目的：明确采用三支架血管内治疗囊状腹主动脉瘤后的血流模式变化。方法：本研究针对7只按既定技术人工构建肾下腹主动脉囊状动脉瘤的长白猪与大白猪开展血流动力学研究。对受试动物实施三支架血管内动脉瘤修复术，分别于支架植入前后采用双功超声扫描评估血流模式，并采用非配对Mann-Whitney检验进行统计学分析。结果：支架植入前的平均收缩期流速为127.4cm/s，术后降至69.81cm/s，差异具有统计学意义。动脉瘤囊内的血流模式亦从湍流转变为支架内层流。结论：采用三支架血管内治疗囊状腹主动脉瘤后，其血流模式可发生明显改变。