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Additional file 5: Table S4. of DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

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Normalized gene expression analysis for selected test tumours and controls. Expression analysis was performed using Affymetrix Human U133_plus2 arrays. Log-transformed expression values are shown for 18 tumour samples (10 diffuse astrocytomas and 8 pilocytic astrocytomas), and foetal and adult normal brain controls (foetal and adult diencephalon, cerebellum and cerebral cortex, adult medulla and thalamus). Affymetrix annotation is shown. Probes are ordered alphabetically according to the gene symbol. (XLSX 19307 kb)

针对选定受试肿瘤与对照样本的标准化基因表达分析。本研究采用Affymetrix人类U133_plus2基因表达芯片完成表达检测。本次展示的为18份肿瘤样本(含10例弥漫性星形细胞瘤与8例毛细胞型星形细胞瘤),以及胎儿与成人正常脑组织对照样本的对数转换后表达值;其中对照样本涵盖胎儿及成人的间脑、小脑、大脑皮层,成人延髓与丘脑。本次分析附带Affymetrix的探针注释信息,探针按照基因符号以字母顺序进行排序。(XLSX格式,文件大小19307 KB)
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2016-12-14
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