CIL:37224

Transmission electron micrograph of nerve cells at the thigh muscle motor end plate. The motor end plate is the highly-excitable region of muscle fiber plasma membrane responsible for initiation of action potentials across the muscles surface and ultimately causing the muscle to contract. Note that this very early (1953) micrograph is primarily of historical interest since it pre-dates glutaraldehye fixation which was introduced in the early 60's and is considered essential for adequate nerve tissue preservation. Examples of nerve tissue micrographs prepared in 1965 are CIL:37218, CIL:37219 and CIL:37220. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.本图像为大腿肌肉运动终板（motor end plate）处神经细胞的透射电子显微图（Transmission electron micrograph）。运动终板是肌纤维质膜上的高兴奋性区域，负责在肌肉表面引发动作电位，最终促使肌肉收缩。需注意，这张拍摄于1953年的早期显微图仅具有历史研究价值，因为其制作时间早于20世纪60年代初引入的戊二醛固定技术——而该技术被认为是实现良好神经组织保存的必要条件。1965年制备的神经组织显微图示例包括CIL:37218、CIL:37219与CIL:37220。本图像由詹姆斯·D·贾米森（James D. Jamieson）与耶鲁大学医学院细胞生物学系提供。