Changes in cellular gene expression during prototype foamy virus infection. Changes in cellular gene expression during prototype foamy virus infection

Changes in cellular gene expression levels in the presence of prototype foamy virus (PFV) infection were analyzed using a transcriptomic sequencing system. The results showed that the greatest changes in cellular gene expression levels were observed after 24h of infection compared to 6h and 12h of PFV infection. These results provide a reference for our study of PFV and host interactions. Overall design: To screen cellular factors involved in PFV replication, we performed transcriptome sequencing on the cellular RNA of PFV-infected HT1080 cells at 6, 12, and 24 h. ** Submitter declares that the raw data are no longer available. ***

本研究借助转录组测序系统，对原型泡沫病毒（prototype foamy virus, PFV）感染条件下宿主细胞的基因表达水平变化进行了分析。结果显示，相较于PFV感染后6小时与12小时，感染后24小时的宿主细胞基因表达水平变化最为显著。上述结果可为PFV与宿主相互作用的相关研究提供重要参考依据。
实验整体设计：为筛选参与PFV复制过程的宿主细胞因子，我们分别于感染后6、12及24小时收取感染PFV的HT1080细胞的RNA并开展转录组测序。
** 提交者声明原始数据已无法获取。 ***