WT mouse transcriptome changes with age. WT mouse transcriptome changes with age

We collected the hypothalamus of mice of different ages to ascertain the biomarkers of aging via comparing the transcriptome changes between old and young WT (C57BL/6J) mice. Overall design: Hypothalamus of three P5 old, three 3-week old, four 4-week old, four 5-week old, three 2-month old, three 6-month old, three 12-month old, three 18-month old and three 24-month old mice.

我们收集了不同年龄小鼠的下丘脑组织，通过对比C57BL/6J品系野生型（Wild Type，缩写WT）老年与年轻小鼠的转录组变化，以探明衰老相关生物标志物。
实验总体设计：分别选取3只出生后5日龄、3只3周龄、4只4周龄、4只5周龄、3只2月龄、3只6月龄、3只12月龄、3只18月龄及3只24月龄小鼠的下丘脑组织。