Bulk RNAseq Analysis of PBMCs from metastatic breast cancer patients. Bulk RNAseq Analysis of PBMCs from metastatic breast cancer patients

The goal of this study is to analyze the blood from patients with metastatic breast cancer to examine the genome of circulating tumor cells that initate metastatic tumors. Overall design: RNA-Seq and single cell RNA sequencing of PBMCs from metastatic breast cancer patients

本研究旨在对转移性乳腺癌患者的血液样本展开分析，以探究启动转移性肿瘤的循环肿瘤细胞（circulating tumor cells）的基因组。实验整体设计：对转移性乳腺癌患者的外周血单个核细胞（peripheral blood mononuclear cells, PBMCs）进行RNA测序（RNA-Seq）与单细胞RNA测序。