遇见数据集

<p>rasuicide_dataset.</p>

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NIAID Data Ecosystem2026-05-10 收录
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Objective This study aimed to determine the prevalence of suicidal ideation among Vietnamese patients with rheumatoid arthritis (RA), and to examine associated factors, other psychiatric disturbances, and quality of life (QoL). Methods A cross-sectional study was conducted from June 2024 to December 2024 at Bach Mai Hospital, Hanoi. Eligible patients met the 1987 ACR classification criteria for RA. Suicidal ideation was assessed through structured psychiatric interviews. Depression, anxiety, insomnia, and sexual dysfunction were evaluated using the PHQ-9, HAM-A, ISI, and ASEX, respectively, while QoL was measured with the EQ-5D-5L. Correlation analyses and structural equation modeling (SEM) explored interrelationships among psychiatric disturbances. Multivariable regression was applied to identify predictors of suicidal ideation, psychiatric symptoms, and QoL. Results Among 187 participants (mean age 56.9 ± 12.7 years; 84.0% female), 13.4% reported suicidal ideation. Anxious (45.5%), insomnia (48.1%) and depressive symptoms (28.3%) were highly common, and depressive, anxiety, and insomnia symptoms were strongly interrelated (e.g., r = 0.74–0.80). The mean EQ-5D-5L index value was 0.6 ± 0.2, indicating moderate impairment in overall QoL. SEM confirmed high correlation between psychiatric (DEP, ANX) and behavioral (SLP, SEX) disturbances. Multivariable analysis showed that high disease activity, joint deformity, and treatment-related adverse effects were consistently associated with suicidal ideation, psychiatric symptoms, and impaired QoL. Conclusion Suicidal ideation and other psychiatric disturbances are commonly observedamong patients with RA in Vietnam. Disease activity, structural damage, and medication-related adverse effects were major determinants, underscoring the need for integrated mental health screening and multidisciplinary management to optimize both clinical and psychosocial outcomes.

研究目的 本研究旨在明确越南类风湿关节炎(Rheumatoid Arthritis, RA)患者的自杀意念患病率,并探讨其相关影响因素、其他精神障碍及生活质量(Quality of Life, QoL)。 研究方法 本研究于2024年6月至2024年12月在河内巴迈医院(Bach Mai Hospital)开展横断面研究。符合纳入标准的患者需满足1987年美国风湿病学会(American College of Rheumatology, ACR)制定的类风湿关节炎分类标准。采用结构化精神访谈评估自杀意念;分别通过患者健康问卷9项(PHQ-9)、汉密尔顿焦虑量表(HAM-A)、阿森斯失眠量表(ISI)与阿森斯性功能评估量表(ASEX)评估抑郁、焦虑、失眠及性功能障碍;采用EQ-5D-5L量表评估生活质量。通过相关性分析与结构方程模型(Structural Equation Modeling, SEM)探究各类精神障碍间的内在关联;采用多变量回归分析识别自杀意念、精神症状与生活质量的预测因素。 研究结果 本研究共纳入187名受试者,平均年龄为56.9±12.7岁,女性占比84.0%;其中13.4%的受试者报告存在自杀意念。焦虑症状(45.5%)、失眠症状(48.1%)与抑郁症状(28.3%)的检出率较高,且抑郁、焦虑与失眠症状间存在显著相关性(相关系数r=0.74~0.80)。EQ-5D-5L指数得分均值为0.6±0.2,提示整体生活质量呈中度受损。结构方程模型证实,精神障碍(抑郁、焦虑)与行为障碍(睡眠、性功能)间存在高度关联。多变量分析显示,高疾病活动度、关节畸形与治疗相关不良反应均与自杀意念、精神症状及生活质量受损显著相关。 研究结论 越南类风湿关节炎患者中,自杀意念与其他精神障碍的检出率普遍较高。疾病活动度、结构性关节损伤与药物相关不良反应是主要影响因素,这提示临床需整合心理健康筛查与多学科管理模式,以优化患者的临床结局与社会心理预后。

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2026-03-09
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