Figure S1 - <i>In Silico</i>, <i>In Vitro</i> and <i>In Vivo</i> Analysis of Binding Affinity between N and C-Domains of <i>Clostridium perfringens</i> Alpha Toxin

Superposition of Cp-PLC (PDB ID: 1CA1) and modelled Cp-PLC N and C-domain complex with N-domain in ribbon format and C-domain in stick format. Cp-PLC N and C-domain residues are colored green and cyan, respectively and N and C-domains of the complex are colored pink and brown, respectively. The shift in orientation of C-domain is showed by arrow. (PPTX)Cp-PLC（PDB编号：1CA1）与建模得到的Cp-PLC N结构域及C结构域复合物的结构叠合结果：复合物的N结构域以丝带展示模式呈现，C结构域以棍状展示模式呈现。原始Cp-PLC的N、C结构域残基分别以绿色、青色标注，该复合物的N、C结构域则分别以粉色、棕色标注。C结构域的取向偏移通过箭头予以示意。 (PPTX)