Data for "Coordination of bacterial cell wall and outer membrane biosynthesis"

Raw data used in the paper "Coordination of bacterial cell wall and outer membrane biosynthesis" by Katherine R. Hummels, Samuel P. Berry, Zhaoqi Li, Atsushi Taguchi, Joseph K. Min, Suzanne Walker, Debora S. Marks, and Thomas G. Bernhardt. These data were collected with the aim of understanding how the lipopolysaccharide biosynthetic enzyme LpxC is regulated in diverse gram-negative bacteria, particularly Pseudomonas aeruginosa. The dataset contains the following tarred directories: <em><strong>Experimental data</strong></em> Microscopy (microscopy.tar.gz) LC-MS/MS (lc-ms_ms.tar.gz) <strong><em>Covariation analysis</em></strong> Multiple sequence alignments (alignments.tar.gz) AlphaFold structures (alphafold.tar.gz) EVcomplex models and couplings (evcomplex.tar.gz) Phylogenetic trees (trees.tar.gz) For more detailed methods and file descriptions, please see README.md. Associated code for analysis can be found at https://github.com/samberry19/evcomplex-interaction-scoring.本数据集为Katherine R. Hummels、Samuel P. Berry、Zhaoqi Li、Atsushi Taguchi、Joseph K. Min、Suzanne Walker、Debora S. Marks及Thomas G. Bernhardt所撰论文《协调细菌细胞壁与外膜生物合成》所使用的原始数据。本数据集的采集旨在解析脂多糖（lipopolysaccharide）生物合成酶LpxC在多种革兰氏阴性菌，尤其是铜绿假单胞菌（Pseudomonas aeruginosa）中的调控机制。数据集包含以下.tar.gz格式打包目录：**_实验数据_**：显微成像数据（microscopy.tar.gz）、液相色谱-串联质谱（LC-MS/MS）数据（lc-ms_ms.tar.gz）；**_共变异分析数据_**：多序列比对文件（alignments.tar.gz）、AlphaFold结构模型（alphafold.tar.gz）、EVcomplex模型与耦合文件（evcomplex.tar.gz）、系统发育树文件（trees.tar.gz）。如需查阅更详细的实验方法与文件说明，请参阅README.md。相关分析代码可通过链接https://github.com/samberry19/evcomplex-interaction-scoring获取。