Memory-induced transcriptome in Huntington's disease (HD) mice [RNA-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE157099
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Evaluation of the effect of procedural memory using the double-H maze (DH) on striatal and hippocampal transcriptome in HD R6/1 mice RNAseq data were generated using the striatum of WT and HD mice in resting condition (home cage, HC), during memory formation (after 2 days of training in the double H maze, DH-2d) and during memory consolidation/recall (after the probe test performed after 4 days of training, DH-5d)
本数据集对应一项评估研究，该研究借助双H迷宫（double-H maze, DH）探究程序性记忆（procedural memory）对亨廷顿舞蹈病（Huntington's Disease, HD）R6/1小鼠纹状体与海马体转录组（transcriptome）的影响；其RNA测序（RNAseq）数据采集自野生型（Wild Type, WT）与HD模型小鼠的纹状体，样本分为三种实验状态：静息状态（饲养笼，home cage, HC）、记忆形成阶段（双H迷宫训练2天后，DH-2d）以及记忆巩固与提取阶段（经4天训练后完成探查试验（probe test），DH-5d）
创建时间：
2025-02-25
