Additional file 1 of Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies

Additional file 1: Table S1. Cancer Site Coding Following SEER and WHO Guidelines. Table S2. Unique Cancer Pairs and Sample Counts in the Kaiser Permanente Research Bank and UK Biobank. Table S3. Sample Counts for Shared Index Cancers Across All Diagnoses in the Kaiser Permanente Research Bank and UK Biobank. Table S4. Single Variant Association Summary Statistics for Multiple Primary Cancers Combined or Grouped by Organ Site. Table S5. Gene-Based Association Summary Statistics for Multiple Primary Cancers Combined or Grouped by Organ Site. Table S6. Single Variant Burden in Individuals with Multiple Versus Single Cancers. Table S7. Gene-Based Burden in Individuals with Multiple Versus Single Cancers.

附加文件1：表S1 遵循SEER（Surveillance, Epidemiology, and End Results Program）与世界卫生组织（WHO）指南的癌症部位编码。表S2 凯撒永久研究库（Kaiser Permanente Research Bank）与英国生物银行（UK Biobank）中的独特癌症配对及样本量统计。表S3 凯撒永久研究库与英国生物银行中，涵盖所有诊断类型的共享索引癌症的样本量统计。表S4 按器官部位合并或分组的多原发癌症的单变异关联汇总统计量。表S5 按器官部位合并或分组的多原发癌症的基于基因的关联汇总统计量。表S6 多发癌症患者与单发癌症患者的单变异负荷情况。表S7 多发癌症患者与单发癌症患者的基于基因的负荷情况。