Additional file 2 of CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway

Additional file 2: Supplementary Table 1. List of 223 common genes from comparison between unique regions by ATAC-seq and differentially upregulated (UP_REG DR) genes by RNA-seq in U937 shCBX2 cells. Supplementary Table 2. List of 25 genes included in the GO molecular function kinase binding (FDR q-value = 1.95 e-9). Supplementary Table 3. List of 334 common genes from comparison between unique regions by ATAC-seq and differentially downregulated (DOWN_REG DR) genes by RNA-seq in U937 shCBX2 cells. Supplementary Table 4. GO biological processes of 334 common genes from comparison between unique regions by ATAC-seq and the differentially downregulated (DOWN_REG DR) genes by RNA-seq in U937 shCBX2 cells. Supplementary Table 5. GO Molecular Function of 334 common genes from comparison between unique regions by ATAC-seq and differentially downregulated (DOWN_REG DR) genes by RNA-seq in U937 shCBX2 cells. Supplementary Table 6. GO KEGG pathways of 334 common genes from comparison between unique regions by ATAC-seq and differentially downregulated (DOWN_REG DR) genes by RNA-seq in U937 shCBX2 cells.附加文件2：补充表1。该表收录U937 shCBX2细胞中，转座酶可及性测序（ATAC-seq）所得独特染色质开放区域与RNA测序（RNA-seq）鉴定的差异上调基因（UP_REG DR）的交集基因，共计223个。 补充表2。该表收录属于基因本体（GO）分子功能条目“激酶结合”的25个基因，其错误发现率q值（FDR q-value）为1.95×10^-9。 补充表3。该表收录U937 shCBX2细胞中，转座酶可及性测序（ATAC-seq）所得独特染色质开放区域与RNA测序（RNA-seq）鉴定的差异下调基因（DOWN_REG DR）的交集基因，共计334个。 补充表4。该表展示上述334个交集基因的基因本体（GO）生物过程富集分析结果，分析基于U937 shCBX2细胞中转座酶可及性测序（ATAC-seq）所得独特染色质开放区域与RNA测序（RNA-seq）鉴定的差异下调基因（DOWN_REG DR）的比较结果。 补充表5。该表展示上述334个交集基因的基因本体（GO）分子功能富集分析结果，分析基于U937 shCBX2细胞中转座酶可及性测序（ATAC-seq）所得独特染色质开放区域与RNA测序（RNA-seq）鉴定的差异下调基因（DOWN_REG DR）的比较结果。 补充表6。该表展示上述334个交集基因的基因本体（GO）与京都基因与基因组百科全书（KEGG）通路富集分析结果，分析基于U937 shCBX2细胞中转座酶可及性测序（ATAC-seq）所得独特染色质开放区域与RNA测序（RNA-seq）鉴定的差异下调基因（DOWN_REG DR）的比较结果。