BAG Barcelona

BAG Barcelona joins 11 groups that belong to two different research institutions: the Institute of Molecular Biology of Barcelona from the Spanish Research Council (IBMB-CSIC) and the Institute for Research in Biomedicine from Barcelona (IRB Barcelona). With a long tradition of accessing the ESRF, the main subjects of research from the BAG groups include protein/DNA complexes, components of viruses, molecular machines, molecular mechanisms of proteases and other enzymes, de-novo design of protein scaffolds and development of crystallopgrahic methods. In this new period, three new research groups have joined the bag: Ferruz lab, Eckhard lab and Guerin lab. The scientific outcomes of all of the groups strongly depend on the acces to high performance beamlines from which to be able to retrieve high-quality structural data. The ESRF offers precisely this together with the exceptional support from their all their scientific staff .

巴塞罗那BAG团队纳入了11个隶属于两家不同研究机构的课题组，这两家机构分别为西班牙国家研究委员会（Spanish Research Council）下属的巴塞罗那分子生物学研究所（Institute of Molecular Biology of Barcelona, IBMB-CSIC），以及巴塞罗那生物医学研究所（Institute for Research in Biomedicine from Barcelona, IRB Barcelona）。长期以来，BAG各课题组拥有使用欧洲同步辐射光源（European Synchrotron Radiation Facility, ESRF）的丰富经验，其核心研究方向涵盖蛋白质/DNA复合物、病毒组分、分子机器、蛋白酶及其他酶类的分子作用机制、蛋白质支架的从头设计，以及晶体学方法开发。在新一轮研究周期中，共有3个全新课题组加入BAG团队，分别为Ferruz实验室、Eckhard实验室与Guerin实验室。所有课题组的科研成果高度依赖高性能同步辐射光束线，以获取高质量的结构生物学数据。ESRF不仅可提供此类光束线资源，还可依托其全体科研人员提供的一流技术支持，为研究工作提供坚实保障。