Overview of cytokine analyses.

Overview of the significant associations of all analyses performed and specified per cytokine. The Mann-Whitney U test was used to compare the groups with each other. Abbreviations: HC: healthy control. 2009 WHO classification: WS-: non-severe dengue without warning signs, WS+: non-severe dengue with warning signs, Sev: severe dengue. Plasma leakage/shock: No : no plasma leakage occured, PL: plasma leakage detected, Hemorrhage: No : no hemorrhagic symptoms, Minor: minor hemorrhage, Sev: severe hemorrhage. Temporal pattern: D1-3: day 1-3 after the onset of fever, D4-7: day 4-7 after the onset of fever, D>7: more than 7 days after the onset of fever. Cluster analysis: * only in a part of the cluster this cytokine is up- or downregulated. Conclusions: CC: clinical classification, CA: cluster analysis.