Additional file 2 of Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health

Additional file 2: Table S1. Complete list of analyzed metabolites, proteins, and clinical parameters. Table S2. Classification and dynamic patterns of 527 analyzed metabolites. Table S3. Functional enrichment analysis of metabolite co-variation clusters. Table S4. Inter- and intra-individual variations of 527 analyzed metabolites. Table S5. Plasma metabolites with significant seasonal variation. Table S6. Temporal patterns of seasonal associated metabolites. Table S7. Pathway enrichment analysis of metabolite co-variation clusters. Table S8. Temporal co-expression patterns of seasonally associated proteins. Table S9. Sex-associated plasma metabolites. Table S10. BMI-associated plasma metabolites. Table S11. Summary of identified independent mQTLs. Table S12. Meta-analysis of identified independent mQTLs. Table S13. Contributions of genetics, lifestyle, and clinical factors to the variability of plasma metabolites. Table S14. Comprehensive mixed-effect modeling analysis of protein-metabolite associations. Table S15. Summary of one-sample mendelian randomization analysis.