Mean of the annual change of total brain volume (%) during the 9-year follow-up period in participants with schizophrenia and control participants.

SD = Standard Deviation.Q1 = first quartile, Q3 = third quartile.aIndependent samples t-test.bAdjusted for sex.cAdjusted for sex, educational level, logarithm of the alcohol use (g/day) and weight change (kg).SD即标准差（Standard Deviation），Q1为第一四分位数（first quartile），Q3为第三四分位数（third quartile）。a 独立样本t检验（Independent samples t-test）。b 已校正性别因素。c 已校正性别、教育水平、酒精使用量（克/天）的对数值以及体重变化量（千克）。