Gene expression profile at single cell level of the whole aorta from human.

To comprehensively study molecular alterations in human aorta tissues,we characterized the cellular heterogeneity of the human aortic wall by performing scRNAseq. We obtained nondiseased ascending aortic wall tissue from 1 heart transplant recipients and 2 heart donor and aortic wall tissue from 3 abdominal aortic aneurysm patients(AAA),3 aortic dissection patients (AD),1 Marfan syndrome patients (MFS) NOTE FROM SUBMITTER: We cannot provide the raw data files due to patient privacy issue

为全面探究人类主动脉组织的分子改变，我们通过单细胞RNA测序（single-cell RNA sequencing, scRNAseq）解析了人类主动脉壁的细胞异质性。我们从1名心脏移植受者、2名心脏供体处获取了无病变的升主动脉壁组织，同时从3名腹主动脉瘤（abdominal aortic aneurysm, AAA）患者、3名主动脉夹层（aortic dissection, AD）患者、1名马凡综合征（Marfan syndrome, MFS）患者处获取主动脉壁组织。提交者备注：受患者隐私保护相关限制，我们无法提供原始数据文件。