FireGate Biotech FG-001: In Silico Systems Analysis Supporting Triplet Mechanistic Complementarity

We performed an in silico systems-level functional association and enrichment analysis using the STRING database to assess whether a curated FG-001 Triplet axis gene/protein set forms a coherent non-random antiviral immune network. The analysis demonstrates highly signifi-cant protein–protein interaction enrichment and strong overrepresentation of antiviral response, interferon-associated innate immunity, and chemokine-mediated trafficking programs. Non-clinical / non-human-subjects: This dataset contains only in silico analyses and database-derived outputs. No clinical trial data, patient-level data, or PHI are included. Related record: Associated figure/report archived on Zenodo https://doi.org/10.5281/zenodo.18355853

本研究借助STRING数据库开展了计算机模拟（in silico）的系统级功能关联与富集分析，以评估经过人工整理的FG-001三联体轴基因/蛋白质集是否能够形成一个连贯且非随机的抗病毒免疫网络。分析结果显示，蛋白质间相互作用存在高度显著的富集现象，同时抗病毒应答、干扰素相关固有免疫以及趋化因子介导的转运通路均呈现显著的过度富集特征。
非临床/非人体受试者研究说明：本数据集仅包含计算机模拟（in silico）分析结果与数据库衍生输出内容，未纳入任何临床试验数据、患者层面数据或受保护健康信息（Protected Health Information，PHI）。
相关记录：关联图表/报告已存档于Zenodo平台，链接为https://doi.org/10.5281/zenodo.18355853