Significantly Associated Variants Confirmed in the Replication Study.

aGenes containing the SNP or the closest gene up to 50 kb up and downstream of the SNP.bOdds ratio for haplotype TDT was calculated based on haplotypes reconstructed from FBAT software viewhap command.cNumber of informative families.dbuild35 rs11711042.a. 包含该单核苷酸多态性（Single Nucleotide Polymorphism，SNP）的基因，或位于该SNP上下游各50 kb范围内的最近邻基因。 b. 单倍型传递不平衡检验（Transmission Disequilibrium Test，TDT）的比值比，基于FBAT软件viewhap命令重构的单倍型进行计算。 c. 信息性家系的数量。 d. 人类基因组组装版本35（build35）中的rs11711042位点。