Supply materials for the network of AD: How to read the network of AD (Text A).
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https://figshare.com/articles/dataset/_Uncovering_the_Molecular_Mechanism_of_Actions_between_Pharmaceuticals_and_Proteins_on_the_AD_Network_/1622777
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资源简介：
The chemical names, functions and the 3D-structures of the 49 enzymes/receptors in the network of AD (Table A). The panel of 31 drugs consisted of 10 AD drugs, 9 diabetes drugs, and 12 heart failure drugs (Table B). The data for 490 complexes formed by 10 AD drugs and 49 proteins (Table C). The data for 441 complexes formed by 9 diabetes drugs and 49 proteins (Table D). The data for 539 complexes formed by 11 diabetes drugs and 49 proteins and the additional 49 complexes formed by the controlling drug amiloride (AMR) and 49 proteins (Table E). The simulation of IC50 data (Figs A-F).
(DOC)
表格A收录了阿尔茨海默病（Alzheimer's Disease，AD）网络内49种酶/受体的化学名称、功能及三维结构数据。表格B收录的31种药物包括10种阿尔茨海默病治疗药物、9种糖尿病治疗药物及12种心力衰竭治疗药物。表格C收录了10种阿尔茨海默病治疗药物与49种蛋白质形成的490个复合物的相关数据。表格D收录了9种糖尿病治疗药物与49种蛋白质形成的441个复合物的相关数据。表格E收录两类数据：其一为11种糖尿病治疗药物与49种蛋白质形成的539个复合物的相关数据；其二为对照药物阿米洛利（Amiloride，AMR）与49种蛋白质形成的额外49个复合物的相关数据。本数据集包含A至F六幅图示展示的半数抑制浓度（IC50）模拟数据。（DOC）
创建时间：
2015-12-11
