Spike-wave seizures and "proepileptic" activity in WAG/Rij rat model of absence epilepsy as recorded in the cortex, hippocampus and thalamus

Version 2 Video-EEG file G8_ed2.avi v.1 is updated: the nomenclature of EEG channels is corrected. Records were taken in 8 months old male WAG/Rij rat during behavioral sleep. Bipolar recordings: Channel 1 (red)- the hippocampus, CA1 (locally); Channel 2 (green) - the ventrobasal thalamus, Po (locally). Monopolar recordings with the reference in the cerebellum: Channel 3 (blue) - the frontal cortex; Channel 4 (green) - the hippocampus, CA1; Channel 5 (red) - the ventrobasal thalamus, Po. Absence seizures (spike-wave discharges) are marked as "SWD" and episodes of "proepileptic" activity are marked as "ProEpi". "Proepileptic" activity appears in the form of rudimentary SWD prior to epileptic SWD or in the form of high voltage spindles during behavioral sleep. SWD are best seen in the monopolar recording in the frontal cortex (blue Channel 3), SWD are also present in the bipolar recordings in the hippocampus (green Channel 4) and the thalamus (red Channel 5), SWD are not seen in the monopolar recording in the hippocampus (red Channel 1).

版本2的视频脑电（Video-EEG）文件G8_ed2.avi v.1已完成更新：修正了脑电（EEG）通道的命名规范。本次记录采集自8月龄雄性WAG/Rij大鼠的行为性睡眠状态。本次记录采用双极记录与单极记录两种采集模式：双极记录：通道1（红色）为局部海马CA1区；通道2（绿色）为局部丘脑腹后核（Po区）。单极记录以小脑作为参考电极：通道3（蓝色）对应额叶皮层；通道4（绿色）对应海马CA1区；通道5（红色）对应丘脑腹后核（Po区）。失神发作（棘慢波放电，spike-wave discharges, SWD）与"致痫前期"活动分别标记为"SWD"与"ProEpi"。其中"致痫前期"活动可表现为癫痫棘慢波放电出现前的雏形棘慢波，或行为性睡眠期间出现的高幅睡眠纺锤波。棘慢波放电在额叶皮层的单极记录（蓝色通道3）中显示最为清晰；在海马（绿色通道4）与丘脑（红色通道5）的双极记录中也可观测到SWD；但在以红色通道1进行的海马区单极记录中无法观察到棘慢波放电。