Substrate-Controlled Regioselective Arylations of 2‑Indolylmethanols with Indoles: Synthesis of Bis(indolyl)methane and 3,3′-Bisindole Derivatives

A substrate-controlled regioselective arylation of 2-indolylmethanols with indoles has been established, which efficiently afforded bis­(indolyl)­methane and 3,3′-bisindole derivatives in high yields and with a broad substrate scope (up to 98% yield, 36 examples). This approach will not only provide an important strategy for the diversified synthesis of bis­(indolyl)­methane and 3,3′-bisindole derivatives but also serve as a good example for substrate-controlled regioselective reactions.