Raw Data - Acute effects of cigarette smoke

Increasing evidence suggests that cigarette smoke exposure could induce VCAM-1 (enhance pro-atherogenicproperty), and a decrease of e-NOS level (anti-atherogenic depletioon). Thus, cigarette smoke may represent a significant risk factor for atherosclerosis by increasing aortic IMT. This evidence is discussed herein.

越来越多的证据表明，香烟烟雾暴露可诱导血管细胞黏附分子1（VCAM-1）表达上调，增强其致动脉粥样硬化特性，并降低内皮型一氧化氮合酶（e-NOS）水平，进而耗竭抗动脉粥样硬化效应。因此，香烟烟雾可通过增加主动脉内膜中层厚度（aortic IMT）成为动脉粥样硬化的重要危险因素。本文将对上述证据进行讨论。