Predicted Cellular Immunity Population Coverage Gaps for SARS-CoV-2 Subunit Vaccines and their Augmentation by Compact Peptide Sets. Liu et al.

This dataset contains computational models and data for the following papers:

Predicted Cellular Immunity Population Coverage Gaps for SARS-CoV-2 Subunit Vaccines and their Augmentation by Compact Peptide Sets
Ge Liu, Brandon Carter, David K. Gifford
Cell Systems, 2020
https://doi.org/10.1016/j.cels.2020.11.010

Computationally Optimized SARS-CoV-2 MHC Class I and II Vaccine Formulations Predicted to Target Human Haplotype Distributions
Ge Liu, Brandon Carter, Trenton Bricken, Siddhartha Jain, Mathias Viard, Mary Carrington, David K. Gifford
Cell Systems, 2020
https://doi.org/10.1016/j.cels.2020.06.009

Additional source code is available at https://github.com/gifford-lab/optivax. Haplotype frequency data are available at http://dx.doi.org/10.17632/cfxkfy9zp4.1

Please cite the relevant papers if you use these data.

本数据集包含以下两篇论文对应的计算模型与实验数据：
新型冠状病毒（SARS-CoV-2）亚单位疫苗的细胞免疫群体覆盖缺口预测及紧凑型肽集的补强作用
Ge Liu, Brandon Carter, David K. Gifford
《细胞系统》（Cell Systems），2020年
https://doi.org/10.1016/j.cels.2020.11.010

经计算优化的、可靶向人类单倍型分布的新型冠状病毒（SARS-CoV-2）主要组织相容性复合体（Major Histocompatibility Complex）I类与II类疫苗配方
Ge Liu, Brandon Carter, Trenton Bricken, Siddhartha Jain, Mathias Viard, Mary Carrington, David K. Gifford
《细胞系统》（Cell Systems），2020年
https://doi.org/10.1016/j.cels.2020.06.009

额外的源代码可于 https://github.com/gifford-lab/optivax 获取。单倍型频率数据可于 http://dx.doi.org/10.17632/cfxkfy9zp4.1 获取。

若使用本数据集的相关数据，请引用对应论文。