Crystal structure of HIV-1 reverse transcriptase with a double stranded DNA in complex with fragment 166 at the transient P-pocket. Descriptor: (1~{R},2~{R})-2-phenyl-~{N}-(1,3-thiazol-2-yl)cyclopropa

Protein Data Bank Japan2024-01-31 更新40

HIV-1 reverse transcriptase with bound fragment at the RNase H primer grip site

HIV-1逆转录酶

片段药物发现

HIV-1 reverse transcriptase with bound fragment at the RNase H primer grip site Descriptor: 1-methyl-5-phenyl-1H-pyrazole-4-carboxylic acid, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyr

Protein Data Bank Japan2023-11-29 更新20

Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms

结构生物学

HIV-1逆转录酶

Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms Descriptor: 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*A

Protein Data Bank Japan2024-11-20 更新50

Crystal structure of HIV-1 K103N mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a

HIV-1逆转录酶

非核苷类抑制剂结合机制

Crystal structure of HIV-1 K103N mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a Descriptor: 1,2-ETHANEDIOL, 4-({4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2-

Protein Data Bank Japan2023-10-04 更新30

+3 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)

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