PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
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PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD) Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION Authors: Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) Deposit date: 2015-06-11 Release date: 2016-07-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Binding and mimicking of the phosphate-rich substrate, PRPP. To be Published
结核分枝杆菌(Mycobacterium tuberculosis)邻氨基苯甲酸磷酸核糖转移酶(Anthranilate phosphoribosyltransferase,AnPRT;trpD)活性位点内结合单个镁离子的PRPP复合物。描述对象:1-O-焦磷酸基-5-O-磷酸基-α-D-呋喃核糖(1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose)、邻氨基苯甲酸磷酸核糖转移酶、镁离子。作者:Evans G.L.、Baker E.N.、Lott J.S.、结核分枝杆菌结构基因组学联盟(TB Structural Genomics Consortium,TBSGC)。提交日期:2015年6月11日;发布日期:2016年7月20日;最后修改日期:2023年9月27日。实验方法:X射线衍射(分辨率2 Å)。引用说明:结合并模拟富含磷酸的底物PRPP,该研究待发表。



