Post-surgical atypical mycobacteriosis in 125 patients in Rio de Janeiro

Abstract INTRODUCTION: The growing incidence of post-surgical atypical mycobacteriosis (PSAM) may be related to the increased use of low- and medium-complexity video-assisted surgery. METHODS: Between April 2007 and June 2009, 125 patients were referred from the State Health Department of Rio de Janeiro for the treatment of confirmed, probable, or suspected PSAM. RESULTS: Laparoscopic cholecystectomy was the most frequent surgical procedure (48.8%) among patients. Clarithromycin, ethambutol, and terizidone were used to treat 113 patients for a mean duration of 226 days. CONCLUSIONS: Despite the need for multidrug therapy and long treatment duration, most included patients adhered to treatment and experienced cure without relapse.

摘要：
引言：术后非典型分枝杆菌感染（post-surgical atypical mycobacteriosis, PSAM）的发病率逐年攀升，或与中低复杂度视频辅助手术的应用增加存在关联。
方法：2007年4月至2009年6月期间，共有125名患者从里约热内卢州卫生厅转诊，接受确诊、疑似或拟诊PSAM的治疗。
结果：患者中最常见的手术方式为腹腔镜胆囊切除术，占比48.8%。113名患者接受了克拉霉素、乙胺丁醇与特立齐酮联合治疗，平均疗程为226天。
结论：尽管需要接受多药联合治疗且疗程较长，但纳入研究的多数患者均依从治疗方案，最终实现治愈且未出现复发。