Data underlying the publication: Quantitative physiology and proteomic adaptations of Bifidobacterium breve NRBB57 at near-zero growth rates

This data set corresponds to the proteome of <em>Bifidobacterium breve</em> NRBB57 which was cultivated at different growth rates from high (0.4 h-1) to near-zero growth rates. The bacteria was cultivated in retentostat and chemostat systems in a media with lactose as energy source. For the proteome analysis, samples were taken from the steady states of 3 biological replicates of the chemostats (µ=0.4 h-1, µ=0.12 h-1, µ=0.05 h-1, µ=0.025 h-1) and from 3 biological replicates of the retentostats after 1, 2 and 3 weeks after connecting the filter. Relative protein quantification was performed by Proteome Discoverer based on peptide intensity signals using default settings. <br>

本数据集对应短双歧杆菌（Bifidobacterium breve）NRBB57的蛋白质组，该菌株以不同生长速率（0.4 h⁻¹的高生长速率至接近零的生长速率）完成培养。该菌株于以乳糖为能源的培养基中，分别在滞留培养（retentostat）和恒化培养（chemostat）系统内进行培养。蛋白质组分析所用样本取自4组不同生长速率的恒化培养稳态，每组均设置3次生物学重复，对应生长速率分别为μ=0.4 h⁻¹、0.12 h⁻¹、0.05 h⁻¹、0.025 h⁻¹；此外还采集了过滤装置连接后第1、2、3周的3次滞留培养生物学重复样本。相对蛋白质定量分析采用Proteome Discoverer软件，基于肽段强度信号并以默认参数完成。