Individualized parameterization of multiparametric monitors alarms in infarcted patients

ABSTRACT Objective: To measure the magnitude of the effect of an individualized parameterization protocol for hemodynamic alarms in patients with acute myocardial infarction. Method: Pragmatic clinical trial, open label and single arm, whose intervention was performed through a protocol validated and tested in 32 patients using multiparametric monitors. The heart rate, blood pressure, respiratory rate, oxygen saturation and ST segment-monitoring were measured and classified for clinical consistency one hour before and after the intervention, for 64 hours. Results: The protocol obtained Content Validity Index of 0.92. Of the 460 registered alarms, 261 were considered inconsistent before the intervention and 47 after it. The Relative Risk of inconsistent alarms after the protocol was 0.32 (95% CI 0.23-0.43, p摘要 研究目的：评估急性心肌梗死患者血流动力学警报（hemodynamic alarms）个体化参数化方案的效应大小。 研究方法：本研究为实用型临床试验，采用开放标签单臂设计，通过一项经多参数监护仪（multiparametric monitors）验证并在32例患者中测试过的方案实施干预。于干预前后1小时起，连续64小时监测心率、血压、呼吸频率、血氧饱和度及ST段，并对其临床一致性进行分类评定。 研究结果：该方案的内容效度指数（Content Validity Index）为0.92。在460条已记录的警报中，干预前有261条被判定为不一致，干预后降至47条。实施该方案后，不一致警报的相对危险度（Relative Risk）为0.32（95%置信区间（Confidence Interval, CI）0.23-0.43，p