Explorative modelling.

To model the effect of the entropy on certain clinical parameters / endpoints, explorative modelling with logistic regression for categorical clinical endpoints (QMG-drop, MMS) and linear regression for clinical endpoints with linear scaling (QMG-score, MG-duration, pre- and postoperative prednisone load) were performed. Respectively, one clinical parameter is thereby modeled on basis of four entropy values (for the number of follicles in the CD23-staining, the follicle grading in the CD23-staining, the grading of the intratyhmic fat and the grading of the atrophy). The table shows the p-value (* indicates significance at the 5%-level) per variable in the adjusted model that contains all the other variables against the respective clinical endpoint.