Local genetic correlations calculated with the ρ-Hess method.

Genomic regions with significant local genetic correlation between BC and lipids using the ρ-Hess method. Only loci that passed Bonferroni correction (P = 0.05/1,703 partitions = 2.9 × 10−5) are shown. Lipid: lipid trait used; Position: genomic coordinates of loci tested (HG19); N_SNPs: number of SNPs in partition; K: number eigenvectors used; Local-rhog: local genetic correlation estimate; Variance: variance estimate; SE: standard error of genetic correlation estimate; Z: Z-score of genetic correlation estimate; P: P-value of genetic correlation estimate. BC, breast cancer. (XLSX)本数据集收录了采用ρ-Hess方法鉴定得到的、乳腺癌与脂质之间存在显著局部遗传相关的基因组区域。仅展示通过邦费罗尼校正（P=0.05/1703个分区=2.9×10⁻⁵）的位点。各字段含义如下： 脂质：所用脂质性状； 位置：所测试位点的基因组坐标（HG19）； N_SNPs：分区内单核苷酸多态性（Single Nucleotide Polymorphism，SNP）的数量； K：所用特征向量的数量； Local-rhog：局部遗传相关估计值； 方差：方差估计值； SE：遗传相关估计值的标准误； Z：遗传相关估计值的Z得分； P：遗传相关估计值的P值。 BC即乳腺癌（breast cancer）。本数据集为XLSX格式。