Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A [ATAC]
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https://www.ncbi.nlm.nih.gov/sra/SRP454086
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Investigating the impact of chr21 amplification in primary patient Lin-Cd34+ cells Overall design: ATAC-sequencing was performed in 5 primary patient chr21amp cells, 4 non-chr21amp primary patient cells and 5 age-matched controls
探讨21号染色体（chr21）扩增对原发性患者Lin⁻CD34⁺细胞的影响
实验设计概述：对5例携带21号染色体扩增的原发性患者Lin⁻CD34⁺细胞、4例未携带21号染色体扩增的原发性患者Lin⁻CD34⁺细胞以及5例年龄匹配的对照样本进行转座酶可及性染色质测序（ATAC-seq）检测
创建时间：
2025-06-27
