Acetolactate Synthase from Klebsiella pneumoniae in Complex with a Reaction Intermediate

Protein Data Bank Japan2023-11-15 更新2026-03-21 收录

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Acetolactate Synthase from Klebsiella pneumoniae in Complex with a Reaction Intermediate Descriptor: (2S,3S)-2,3-dihydroxy-3-[(7S,8R,9aS)-8-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2,7-dimethyl-5,7,8,10-tetrahydro-9aH-pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin-9a-yl]-2-methylbutanoic acid, Acetolactate synthase, catabolic, ... Authors: Latta, A.J, Andrews, F.H, McLeish, M.J. Deposit date: 2017-07-05 Release date: 2018-07-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Acetolactate Synthase from Klebsiella pneumoniae in Complex with Mechanism-Based Inhibitor To Be Published

肺炎克雷伯菌（Klebsiella pneumoniae）来源的乙酰乳酸合酶（Acetolactate Synthase）与反应中间体复合物的结构描述：配体为(2S,3S)-2,3-二羟基-3-[(7S,8R,9aS)-8-(2-{[(R)-羟基(膦酰氧基)膦酰基]氧基}乙基)-2,7-二甲基-5,7,8,10-四氢-9aH-嘧啶并[4,5-d][1,3]噻唑并[3,2-a]嘧啶-9a-基]-2-甲基丁酸；该酶为分解代谢型乙酰乳酸合酶……作者：Latta, A.J.、Andrews, F.H.、McLeish, M.J. 存档日期：2017-07-05 发布日期：2018-07-11 最后修改日期：2023-11-15 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.12埃引用文献：《肺炎克雷伯菌来源的乙酰乳酸合酶与基于机制的抑制剂复合物》待发表

创建时间：

2017-07-05