Data_Sheet_1_Textiles impregnated with antimicrobial substances in healthcare services: systematic review.pdf

BackgroundAntimicrobial textiles have proved to be a promising biosafety strategy. Thus, the current study was focused on identifying which antimicrobial substances impregnated in textiles used in healthcare services confer efficacy in reducing the microbial load present in these textiles and/or the Healthcare-Associated Infection (HAI) rates, when compared to conventional textiles.
MethodsA systematic review of intervention studies using MEDLINE via the PubMed portal, EMBASE, CINAHL, Web of Science, Scopus, Google Scholar and medRxiv. The studies identified were selected according to eligibility criteria and submitted to data extraction and methodological quality evaluation through Joanna Briggs Institute specific tools. The outcomes were synthesized qualitatively.
Results23 studies were selected to comprise the final sample, in which antimicrobial textiles were used by hospitalized patients, by health professionals during work shifts and in inanimate healthcare environments.
ConclusionsCopper, silver, zinc oxide, titanium and silver-doped titanium impregnated in textiles used by patients confer efficacy in reducing the microbial load of these textiles and/or the HAI rates. Quaternary ammonium, chlorhexidine, silver and copper together, quaternary ammonium, alcohols and isothiazolone derivatives together, chitosan and dimethylol dimethyl hydantoin together, all impregnated in textiles used by health professionals confer efficacy in reducing the microbial load of these textiles. Quaternary ammonium impregnated in textiles used in inanimate healthcare environments confers efficacy in reducing the microbial load of these textiles.

背景 抗菌纺织品已被证实是一种极具前景的生物安全策略。因此，本研究旨在明确：相较于常规纺织品，医疗服务场景中使用的浸渍了何种抗菌物质的纺织品，可有效降低自身表面的微生物负荷，以及/或降低医院获得性感染（Healthcare-Associated Infection, HAI）发生率。
方法 本研究对PubMed门户（MEDLINE）、EMBASE、CINAHL、Web of Science、Scopus、Google Scholar及medRxiv收录的干预性研究进行系统综述。根据纳入排除标准筛选已识别的研究，随后通过乔安娜·布里格斯研究所（Joanna Briggs Institute）专用工具开展数据提取与方法学质量评价，并对研究结果进行定性综合。
结果 最终纳入23项研究作为最终样本，这些研究涉及的抗菌纺织品使用场景包括：住院患者使用、医护人员轮班期间使用，以及医疗环境中非生命物体表面使用。
结论 住院患者使用的浸渍了铜、银、氧化锌、钛及银掺杂钛的纺织品，可有效降低自身表面的微生物负荷，以及/或降低医院获得性感染发生率。医护人员使用的浸渍了季铵盐、氯己定、银与铜复配物、季铵盐与醇类及异噻唑啉酮衍生物复配物、壳聚糖以及二羟甲基二甲基乙内酰脲复配物的纺织品，可有效降低自身表面的微生物负荷。医疗环境中非生命物体表面使用的浸渍了季铵盐的纺织品，可有效降低自身表面的微生物负荷。