Performance of PAINTOR compared to standard methodologies at variable sized loci.
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To expedite simulations, we used a modified version of the simulation setup. As before, causal SNPs were drawn according to a logistic prior such that in expectation there were a total of 100 causal variants – we did not enrich causal in any annotations. For this experiment, Z-scores were drawn directly from a multivariate normal distribution; this gave virtually identical results to using simulated genotypes derived from HAPGEN (see Methods). We find that PAINTOR increasingly outperforms existing methodologies as the size of the loci become larger.Performance of PAINTOR compared to standard methodologies at variable sized loci.
创建时间：
2015-12-02
