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In-transit extremity melanoma III
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创建时间：
2011-12-22
相关数据集
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance.
The epigenetic regulator BMI1 is upregulated in many human malignancies and has been implicated in cell migration, but the impact on autochthonous tumor progression is unexplored. Our analyses of huma
NIAID Data Ecosystem70
Metastatic potential in clonal melanomal cells is driven by a rare, early-invading subpopulation [RNA-Seq]
To investigate the molecular basis driving a highly invasive phenotype of a rare subpopulation of melanoma cells; The highly invasive phenotype was regulated by the NKX2.2 transcription factor and it
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Stromal lipid species dictate melanoma metastasis and tropism [MeWo_RNA_seq]
Cancer cells adapt to signals in the tumor microenvironment (TME), but the TME cues that impact metastasis and tropism are unknown. We show that stromal lipids from young adipocytes are taken up by me
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Stromal lipid species dictate melanoma metastasis and tropism [MeWo_RNA_seq]. Stromal lipid species dictate melanoma metastasis and tropism [MeWo_RNA_seq]
Cancer cells adapt to signals in the tumor microenvironment (TME), but the TME cues that impact metastasis and tropism are unknown. We show that stromal lipids from young adipocytes are taken up by me
NIAID Data Ecosystem30
L1CAM knockdown significantly reduces metastasis in a xenograft model of human melanoma
As L1CAM expression is associated with metastasis in melanoma patients, it could be a target for the combination therapies. We investigated the functional role of L1CAM in melanoma metastasis by the
NIAID Data Ecosystem30
