Gut Microbiome Signatures Associated with Breast Cancer in an Indian Cohort

This study profiles the gut microbiota of Indian breast cancer patients and healthy controls using 16S rRNA V3-V4 amplicon sequencing. Fecal DNA from 22 breast cancer patients and 30 healthy women was analyzed to assess bacterial diversity and identify differentially abundant taxa. The dataset provides insight into breast cancer associated gut microbial alterations in an Indian population and supports future research on host microbe interactions and microbial biomarkers of disease progression. Data generated and submitted by Srinidhi Narayani Seenivasan, KMCH Research Foundation, under the supervision of Dr. Velmurugan Ganesan

本研究采用16S rRNA V3-V4区扩增子测序技术，对印度乳腺癌患者及健康对照人群的肠道菌群展开表征分析。本研究针对22名乳腺癌患者与30名健康女性的粪便DNA样本进行测序分析，以评估细菌群落多样性并鉴定差异丰度分类群。本数据集可为解析印度人群中与乳腺癌相关的肠道菌群改变提供重要研究视角，同时为后续宿主-微生物互作及疾病进展相关微生物标志物的相关研究提供有力支撑。本数据集由供职于KMCH研究基金会（KMCH Research Foundation）的斯里尼迪·纳拉亚尼·西尼瓦桑（Srinidhi Narayani Seenivasan），在韦卢穆鲁根·加内桑博士的指导下生成并提交。