Hippocampal CA1 sequencing of ovariectomized mice

To elucidate the mechanism of ERbeta underlying CA1 neuronal excitability involved in the increased susceptibility to the epilepsy of OVX mice, the high throughput RNA seq was performed to identify genes with altered expressions.

为阐明雌激素β受体（ERbeta）介导与去卵巢小鼠（OVX mice）癫痫易感性升高相关的海马CA1区神经元兴奋性的潜在机制，本研究通过高通量RNA测序（RNA-seq）筛选差异表达基因。