Effect of type 2 diabetes on transcriptional signatures during exercise and recovery

We performed gene expression microarray analysis of skeletal muscle biopsies from normal glucose tolerant subjects and type 2 diabetes subjects obtained during a 60 min bicycle ergometer exercise and the 180 min of recovery phase We analysed skeletal mucle biopsies from patients with T2D and from control subjects (n=7 each) at three time points during exercise and recovery

本研究对糖耐量正常（对照）受试者与2型糖尿病（type 2 diabetes, T2D）患者的骨骼肌活检标本开展了基因表达微阵列分析，上述标本采集自60分钟功率自行车运动期间及后续180分钟的恢复阶段。本研究同时于运动及恢复阶段的三个时间点采集两组受试者的骨骼肌活检标本并进行分析，每组各7例。