Ancylostoma caninum Genome Sequencing. Ancylostoma caninum strain:Baltimore

The Genome Institute and collaborators are sequencing the dog hookworm, Ancylostoma caninum. Hookworm diseases are extremely common in the tropics and sub-tropics, with a disease burden comparable to measles and exceeding that of diabetes and lung cancer. A. caninum causes disease in dogs resulting often in severe anemia and death. This species, which belongs to the group of parasites most closely related to C. elegans, is a widely used model for hookworm infection.

基因组研究所及其合作团队正针对犬钩虫（Ancylostoma caninum）开展测序工作。钩虫病在热带与亚热带地区广泛流行，其疾病负担可与麻疹相媲美，甚至超过糖尿病与肺癌的疾病负担。犬钩虫可引发犬类疾病，常导致严重贫血乃至死亡。该物种隶属于与秀丽隐杆线虫（C. elegans）亲缘关系最为密切的寄生虫类群，是钩虫感染研究中广泛使用的模型生物。