EasyFuse detected fusion gene candidates

This dataset contains supplementary data tables with predicted gene fusion candidates from the EasyFuse publication Weber et al. 2022<br><br><br>File 1: Fusion genes detected in MCF7 and SKBR3 cell lines.<br>Presented are fusion genes detected in MCF7 and SKBR3 sequencing samples: Each breakpoint pair combined with the overlapping gene names and reading strands in reading direction represents a prediction as indicated in column “FGID”, as well separately in the columns “BPID, “Fusion_Gene”, “Breakpoint1” and “Breakpoint2”. Genomic coordinates refer to human reference genome hg38. Junction reads and spanning pairs reported by the detection tools are presented in column “Junction_Reads” and “Spanning_Reads”. The “Sample” column indicates the cell line and the column “Tool” the reporting tool. The column “Prediction_File” contains information on the sequencing replicate used for prediction.<br><br>File 2: Fusion genes detected in FF tumor tissue<br>Fusion genes detected in 14 FF breast cancer samples. Each breakpoint pair combined with the overlapping gene names and reading strands in reading direction represents a prediction as indicated in column “FGID”, as well separately in the columns “BPID”, “Fusion_Gene”, “Breakpoint1” and “Breakpoint2”. Genomic coordinates refer to human reference genome hg38. Junction reads and spanning pairs reported by the detection tools are presented in column “Junction_Reads” and “Spanning_Reads”. The “Sample” column indicates the cell line and the column “Tool” the reporting tool. The column “Prediction_File” contains information on the sequencing replicate used for prediction.<br><br>File 3: Fusion genes detected in FF normal tissue<br>Fusion genes detected in 143 normal tissue samples derived from 49 different tissue sites. Each detected breakpoint pair combined with reading strands represents a prediction as indicated in column “BPID”. Genomic coordinates refer to human reference genome hg38. Junction reads and spanning pairs reported by the detection tools are presented in column “Junction_Reads” and “Spanning_Reads” and the reporting tool in column “Tool”. The “Sample” column indicates the sample ID with the tissue site given in “Tissue”.<br><br>File 4: EasyFuse predicted fusion genes in FF tumor tissue<br>EasyFuse output of predicted candidate fusion genes in 57 breast cancer samples. For a detailed description of the columns, please refer to the description of the EasyFuse output format in the methods.<br><br>File 5: EasyFuse detected fusion genes in FFPE tumor tissue<br>EasyFuse output of predicted candidate fusion genes in 14 FFPE tumor samples. For a detailed description of the columns, please refer to the description of the EasyFuse output format in the methods.<br><br><br>File 6: EasyFuse detected fusion genes in the immunogenicity cohort<br>EasyFuse output of predicted candidate fusion genes in 14 FFPE tumor samples. For a detailed description of the columns, please refer to the description of the EasyFuse output format in the Methods.<br><br>本数据集包含Weber等人2022年发表的EasyFuse研究中预测基因融合候选物的补充数据表。 文件1：MCF7与SKBR3细胞系中检测到的融合基因 本文件呈现了MCF7和SKBR3测序样本中检测到的融合基因：每个断点对结合重叠基因名称及阅读方向上的转录链，均以"FGID"列标注为一条预测结果，同时也可分别通过"BPID"、"Fusion_Gene"、"Breakpoint1"及"Breakpoint2"列查看详细信息。基因组坐标参照人类参考基因组hg38。检测工具所报告的连接读数（Junction reads）与跨接读段对（spanning pairs）分别列于"Junction_Reads"与"Spanning_Reads"字段中。"Sample"列标注对应细胞系，"Tool"列标注用于检测的工具，"Prediction_File"列则包含用于预测的测序重复样本相关信息。 文件2：福尔马林固定（Formalin-Fixed, FF）肿瘤组织中检测到的融合基因 本文件包含14份福尔马林固定（FF）乳腺癌样本中检测到的融合基因。每条预测结果均由断点对结合重叠基因名称及阅读方向上的转录链构成，以"FGID"列标注，也可分别通过"BPID"、"Fusion_Gene"、"Breakpoint1"及"Breakpoint2"列查看。基因组坐标参照人类参考基因组hg38。检测工具所报告的连接读数与跨接读段对分别列于"Junction_Reads"与"Spanning_Reads"字段。"Sample"列标注对应细胞系，"Tool"列标注检测工具，"Prediction_File"列包含用于预测的测序重复样本相关信息。 文件3：福尔马林固定（FF）正常组织中检测到的融合基因 本文件包含来自49种不同组织部位的143份正常组织样本中检测到的融合基因。每个检测到的断点对结合转录链构成一条预测结果，以"BPID"列标注。基因组坐标参照人类参考基因组hg38。检测工具所报告的连接读数与跨接读段对分别列于"Junction_Reads"与"Spanning_Reads"字段，检测工具信息则列于"Tool"列。"Sample"列标注样本ID，"Tissue"列标注对应组织部位。 文件4：福尔马林固定肿瘤组织中EasyFuse预测的融合基因 本文件为57份乳腺癌样本中预测的候选融合基因的EasyFuse输出结果。关于各列的详细说明，请参阅研究方法中EasyFuse输出格式的相关描述。 文件5：福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）肿瘤组织中EasyFuse检测到的融合基因 本文件为14份福尔马林固定石蜡包埋（FFPE）肿瘤样本中预测的候选融合基因的EasyFuse输出结果。关于各列的详细说明，请参阅研究方法中EasyFuse输出格式的相关描述。 文件6：免疫原性队列中EasyFuse检测到的融合基因 本文件为14份福尔马林固定石蜡包埋（FFPE）肿瘤样本中预测的候选融合基因的EasyFuse输出结果。关于各列的详细说明，请参阅研究方法中EasyFuse输出格式的相关描述。