Pd(II)-Catalyzed Synthesis of Benzisoxazolones from Benzohydroxamic Acids via C–H Activation

A Pd-catalyzed method for the synthesis of benzisoxazolones
from
benzohydroxamic acids using Oxone as an oxidant in a one-pot procedure
has been developed. In this process, the reaction appears to be suitable
for construction of various benzisoxazolones.

本研究开发了一种以过一硫酸氢钾复合盐（Oxone）为氧化剂、苯并羟肟酸（benzohydroxamic acids）为原料，通过钯（Pd）催化的一锅法合成苯并异恶唑酮（benzisoxazolones）的方法。该反应可适用于构建多种苯并异恶唑酮类化合物。