Genome sequencing of Clostridium botulinum isolates

The increasing availability of C. botulinum genome sequences is starting to allow the genomic diversity of C. botulinum Groups I, II and III to be characterised. This information will impact on microbiological food safety through improved surveillance and tracing/tracking during outbreaks, including the risk presented, and new insights into their biology, food chain transmission, and evolution.

肉毒梭菌（Clostridium botulinum）基因组序列的日益丰富，正使得我们得以对I、II、III群肉毒梭菌的基因组多样性进行表征与解析。此类信息将通过强化疫情暴发期间的监测与溯源追踪工作、明确其引发的感染风险，以及为其生物学特性、食物链传播途径及进化历程提供全新认知，对微生物食品安全领域产生重要影响。