Data from: Wound healing splinting devices for faster access and use

This dataset contains information on silicone wound splinting devices designed for use in excisional wound healing models in mice. The data includes:
-Specifications for Titanium and aPDMS wound splints of various sizes and shapes
- Manufacturing methods and materials used to produce the splints
- Sterilization protocols for the splints
-Instructions for surgical application of the splints in mouse models
-Wound healing outcomes data from experiments using the splints, including:
**Wound closure rates
**Histological analysis of wound tissues
**Images and measurements of wounds over time with and without splints applied
**Data was collected through laboratory experiments conducted at Duke University between 2022-2024.
Wound measurements were taken using digital Celestron Camera and wound imaging software. Histological samples were processed using standard protocols and analyzed with light microscopy.

This dataset provides information to enable researchers to reproduce the silicone splint manufacturing process and experimental wound healing model. The wound healing outcome data demonstrates the effects of using the splinting devices compared to non-splinted controls.

本数据集收录了用于小鼠切除伤口愈合模型的硅胶伤口固定装置相关信息。
所涵盖的数据内容如下：
- 不同尺寸与形态的钛合金及改性聚二甲基硅氧烷（aPDMS）伤口固定装置规格参数
- 该固定装置的制备工艺与所用原材料
- 固定装置的灭菌操作规程
- 小鼠模型中该装置的手术植入操作指南
- 采用该装置开展的实验所得伤口愈合结局数据，具体包括：
- 伤口闭合率
- 伤口组织的组织学分析结果
- 有无固定装置时不同时间点的伤口图像与量化测量数据

本数据集的实验数据采集自2022至2024年间于杜克大学（Duke University）开展的实验室研究。伤口测量采用数码星特朗（Celestron）相机及伤口成像软件完成；组织学样本按照标准流程制备，并通过光学显微镜进行分析。

本数据集可为研究人员复刻硅胶固定装置的制备流程与实验性伤口愈合模型提供完整信息，其收录的伤口愈合结局数据可对比展示固定装置组与未固定对照组的使用效果差异。