Selected genes whose inactivation strongly aggravates formation of SOD-YFP neuronal inclusions1.

120 genes out of the 88 hits from the screen are listed here.2RNAi scores range from 1 to 5, with 5 representing the strongest increase of the G85R-YFP inclusions, and 1 a discernible increase.3Alleles are loss-of-function mutations that have been bred to homozygosity in the strain carrying the G85R-YFP transgene; ��+�� represents moderate increase of the inclusion profile, and ��++�� strong increase.1. 本次遗传筛选得到的88个命中基因中，有120个基因在此列出。 2. RNA干扰（RNAi）评分的取值范围为1至5，其中5代表G85R-YFP包涵体的增强程度最强，1代表可观测到的轻度增强。 3. 所涉及的等位基因为功能丧失型突变（loss-of-function mutation），已在携带G85R-YFP转基因（transgene）的菌株中培育至纯合状态；"+"代表包涵体特征的中度增强，"++"代表显著增强。