Replication Data for: Neutrophil to lymphocyte ratio as a prognostic and mortality marker in COVID-19 infection

In our clinical experience, HRCT Scan Chest is the best diagnostic and prognostic tool in COVID-19 infection. However, this is expensive and associated with significant radiation exposure. We carried out this study to determine the role of neutrophil to lymphocyte ratio (NLR) at the time of admission as an alternative marker. We found a significant relationship between NLR and CT severity score. NLR at a cut off of 2.42 had sensitivity of 81.58% and specificity 77.54% for predicting clinically severe disease. NLR at a cut off of 4.26 had sensitivity of 94.74% and specificity 85.99% for predicting mortality. The results of this study prove that this easily available and cost effective marker can be used to utilize healthcare resources equitably during the pandemic.

在临床实践中，胸部HRCT扫描（HRCT Scan Chest）是新型冠状病毒肺炎（COVID-19）感染的最佳诊断及预后评估工具。然而该检查成本高昂，且伴随显著的辐射暴露风险。本研究旨在明确入院时的中性粒细胞与淋巴细胞比值（NLR）作为替代标志物的临床价值。研究发现，NLR与CT严重度评分存在显著相关性。当NLR截断值为2.42时，其预测临床重症疾病的灵敏度为81.58%、特异度为77.54%；当NLR截断值为4.26时，其预测患者死亡的灵敏度为94.74%、特异度为85.99%。本研究结果证实，这一易于获取且成本低廉的标志物可用于疫情期间医疗资源的公平合理配置。