Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane

Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane Descriptor: (5R)-1-methyl-7-[5-(propan-2-yloxy)pyridin-3-yl]-1,7-diazaspiro[4.4]nonane, MAGNESIUM ION, SULFATE ION, ... Authors: Bobango, J, Wu, J, Talley, T.T. Deposit date: 2015-04-29 Release date: 2015-05-13 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.901 Å) Cite: Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane. To be Published

加州海兔（Aplysia californica）来源的嵌合乙酰胆碱结合蛋白（Ac-AChBP）的晶体结构，该蛋白携带来自人源α3烟碱型乙酰胆碱受体的C环，并与7-(5-异丙氧基吡啶-3-基)-1-甲基-1,7-二氮杂螺环[4.4]壬烷形成复合物。配体描述：(5R)-1-甲基-7-[5-(丙-2-氧基)吡啶-3-基]-1,7-二氮杂螺环[4.4]壬烷、镁离子、硫酸根离子……作者：Bobango, J、Wu, J、Talley, T.T. 保藏日期：2015-04-29 发布日期：2015-05-13 最后修改日期：2024-10-16 检测方法：X射线衍射（分辨率1.901埃）引用信息：加州海兔来源的嵌合乙酰胆碱结合蛋白（Ac-AChBP，携带来自人源α3烟碱型乙酰胆碱受体C环）与7-(5-异丙氧基吡啶-3-基)-1-甲基-1,7-二氮杂螺环[4.4]壬烷复合物的晶体结构，待发表