A familial study of a de novo FGG gene mutation causing congenital hypofibrinogenaemia and intervention during pregnancy and childbirth

To investigate the family line of a pregnant woman with congenital hypofibrinogenaemia due to a de novo mutation in the fibrinogen gamma (FGG) gene and experimentally explore its molecular pathological mechanisms.

本研究旨在探究1例因纤维蛋白原γ（FGG）基因新发突变导致的先天性低纤维蛋白原血症孕妇的家族谱系，并通过实验手段探索其分子病理机制。