Anticholinergic toxicity in a one-year-old male following ingestion of Lupinus mutabilis seeds: case report

ABSTRACT CONTEXT: The seeds from Lupinus mutabilis Sweet, also called “chocho”, are an important part of the diet in several countries in South America. Prior to consumption, processing is required to remove toxic alkaloids. These alkaloids are known to have pharmacological properties as antiarrhythmics, antimuscarinics and hypoglycemics. CASE REPORT: We report a case in which a one-year-old male initially presented with altered mental status and respiratory distress and subsequently developed symptoms of anticholinergic toxicity, after ingesting a large amount of chocho seeds. CONCLUSION: In spite of going through a difficult clinical condition, the subject evolved favorably through receiving supportive treatment. The seeds from Lupinus mutabilis provide nutritional benefits when consumed, but people need to know their risks when these seeds are consumed without proper preparation.背景摘要：甜羽扇豆（Lupinus mutabilis Sweet）的种子俗称“巧豆（chocho）”，是南美多国饮食中的重要组成部分。食用前需经加工以去除其中的有毒生物碱，这类生物碱已被证实具有抗心律失常药、抗胆碱药及降糖药的药理活性。 病例报告：本次报告一则病例：一名1岁男性幼儿在大量误食巧豆种子后，最初表现为意识状态改变与呼吸窘迫，随后出现抗胆碱能中毒症状。 结论：尽管该患者曾经历危重临床状况，但通过接受支持治疗后病情得到良好转归。甜羽扇豆种子在正确食用时可提供营养益处，但如若未经过适当处理即食用，其潜藏风险需为民众所知晓。