Association of sentinel SNPs with two steroid conjugates in three cohorts.

Association of sentinel SNPs with steroid glucuronide levels in two published studies and in the ARIC cohort. According to 1000 Genome Project, European population, these SNPs (rs78176967, rs61285056 and rs151042642) are in strong LD with one another (D’ = 1, r2>0.95). The A1 and A2 alleles are on the minus strand. The primary data are available through the established dbGaP application procedure for the ARIC study (dbGaP Study Accession: phs000280.v5.p1).本数据集涵盖两项已发表研究及ARIC队列中，哨兵单核苷酸多态性（Single Nucleotide Polymorphism, SNP）与类固醇葡萄糖醛酸苷水平的关联分析内容。基于千人基因组计划（1000 Genomes Project）的欧洲人群数据，上述SNP（rs78176967、rs61285056及rs151042642）彼此间存在强连锁不平衡（Linkage Disequilibrium, LD；D’=1，r²>0.95）。A1与A2等位基因位于负链上。本研究的原始数据可通过ARIC研究既定的dbGaP申请流程获取（dbGaP研究收录号：phs000280.v5.p1）。